Cancer (tagged articles)Cancer Epidemiology in Romani-Americans: A Review of the Current LiteratureNaszrin Arani - Romanies are one of history’s most misunderstood ethnic populations. Since medieval times, they have faced slavery, forced assimilation, sterilization, genocide, and other forms of ethnic cleansing. Their cultural and historical persecution has led to adverse... Keep Reading »
Genetic Coevolution: Transposable Elements and their Impact on Disease Development in HumansGillian K. McNeil - Transposable elements (TEs), also referred to as ‘jumping genes’, are sequences of DNA located in the eukaryotic genome that have the ability to mobilize. This functional mobilization allows TEs to insert at random positions throughout the genome. It is... Keep Reading »
Causal Inference to Ascertain Causes of Metastasis in MelanomaWesley Maddox - Causal inference methods were performed on The Cancer Genome Atlas (TCGA) clinical datasets. First, relevant patient data were collected and merged. Then, an algorithm was used to create a causal directed acyclic graph (DAG). Next, the Iterative Deep A* (IDA) algorithm... Keep Reading »
The Importance of the Ras-Raf Pathway in Cancer DevelopmentGina M. Kelley - The Ras/Raf pathway is a crucial cell signaling pathway utilized by eukaryotic cells for growth and proliferation, and it is highly conserved amongst all eukaryotic organisms. Mutations in this pathway lead to uncontrolled growth and proliferation of cancerous cells... Keep Reading »
Gene Therapy: Current Treatment Options and Likely Near-Term DevelopmentsMark T. Edwards - Gene therapy has ceased to be a futuristic dream and instead become a treatment for the present. Somatic cells can be treated with gene replacements or gene fragments to express required proteins and whilst gene therapy was originally aimed at inherited disease, it... Keep Reading »
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